Files are available under licenses specified on their description page. Pdf antifungal property and phytochemical screening of the crude. Absolute configurations were assigned by careful comparison of their specific optical rotation. Introduction the cumulative effect of increased free radicals, especially reactive oxygen species ros and reactive nitrogen species rns is the cause of several chronical and degenerative diseases 14. The methanol leaf extract of mallotus oppositifolius was evaluated for. Bioactive phloroglucinols from mallotus oppositifolius. Despite the use of mallotus oppositifolius in treating psychiatric and affective disorders in ghana, there is no scientific data on its antidepressant effect. Thus the present study investigated the effect of the hydroalcoholic leaf extract of the plant in acute antidepressant modelsthe forced swim fst and tail suspension tests tst. The antioxidant activity was done in vitro using ferric reducing antioxidant power frap and 1,1diphenyl2hydrazyl. The methanol leaf extract of mallotus oppositifolius was evaluated for anti inflammatory activity in rats and mice using acute and chronic antiinflammatory. Mallotus oppositifolius pdf the methanol leaf extract of mallotus oppositifolius was evaluated for anti inflammatory activity in rats and mice using acute and chronic. The structures of the new compounds were determined on the basis of spectroscopic evidence, including. Evaluation of mallotus oppositifolius methanol leaf extract on the. African journal of biotechnology 2 the rats were fasted overnight before experimentation but were allowed free access to water.
The mallotus oppositifolius nyanyafrowais one the oldest. Antibacterial phloroglucinols derivatives from the leaves. This information is available free of charge via the internet at. Here, we used pharmacological screening and electrophysiological analysis in combination with in silico docking and sitedirected mutagenesis to elucidate the effects of m. Apr 18, 2015 this page was last edited on 18 april 2015, at 20. These channels, which transport positively charged atoms ions of potassium out of cells, play key roles in a cells ability to generate and transmit electrical signals.
Research article antidepressant effects of mallotus oppositifolius in acute murine models kennedyk. Dpph scavenging activity of mallotus oppositifolius. Comparative morphological, anatomical and phytochemical studies on two species of euphorbiaceae m. However, it must be distinguished from kamala meaning lotus in many indian languages, an unrelated plant, flower, and sometimes metonymic spiritual or artistic concept. Diabetes which is associated with impaired glucose metabolism leads to oxidative stress which with an attendant protein glycation will produce free radicals 19. The mallotus oppositifolius nyanyafrowa is one of the oldest tree in the forest but its height and stature remains the same even after a thousand years. Antiinflammatory and antioxidant activities of mallotus oppositifolius. Mallotus oppositifolius is a shrub that is used traditionally to treat epilepsy, but its potential has not been scientifically validated. Please note that this is a trial program and may end. Mansonia kamerunica asosong mh dec feb forests tree with white flowers, sweet fruits attract bees 16 81. Oct 29, 2019 mallotus oppositifolius filed as glinus oppositifolius l.
The pdf file you selected should load here if your web browser has a pdf reader plugin installed for example, a recent version of adobe acrobat reader if you would like more information about how to print, save, and work with pdfs, highwire press provides a helpful frequently asked questions about pdfs. The structures of the new compounds were determined on the basis of spectroscopic evidence, including their 1d. Locally it is known as sroti in ewe or strataduca in akan burkill, 1985. Mallotus oppositifolius is a plant species in the genus mallotus found in africa and madagascar. The methanol leaf extract of mallotus oppositifolius was evaluated for antiinflammatory activity in rats and mice using acute and chronic antiinflammatory models with acetylsalicylate acid aspirin as the reference drug. Jun 19, 2019 the methanol leaf extract of mallotus oppositifolius was evaluated for anti inflammatory activity in rats and mice using acute and chronic antiinflammatory. This article cites 44 articles, 10 of which you can access for free. It has a short, and often fluted bole that can be up to 50cm in diameter, but is usually much less. An mallotus oppositifolius in nahilalakip ha genus nga mallotus, ngan familia nga euphorbiaceae. Access is allocated within two business days of purchase and lasts one year. Research article antidepressant effects of mallotus. Mangifera indica anacardiaceae pl, ja arbre fr, me 21 80. Until now, the molecular mechanism was not completely understood.
Research article evaluation of mallotus oppositifolius methanol leaf extract on the glycaemia and lipid peroxidation in alloxaninduced diabetic rats. Bioassayguided fractionation of an ethanol extract of the leaves and inflorescence of mallotus oppositifolius collected in madagascar led to the isolation of the two new bioactive dimeric phloroglucinols mallotojaponins b 1 and c 2, together with the known mallotophenone 3. Pdf antidepressant effects of mallotus oppositifolius in. Racemic compounds 1 and 2 were separated by chiralphase hplc, and the. Preliminary phytochemical screening conducted on the crude methanol and aqueous extracts of the plant revealed the presence of alkaloids, flavonoids, saponins, tannins, steroids, cardiac glycosides and terpenoids in both extracts of the plant. Free fulltext pdf articles from hundreds of disciplines, all in one place.
Beeloving plants for honey food and agriculture organization. The bole is around 10cm in diameter, usually branching from low down. Antiproliferative and antiplasmodial dimeric phloroglucinols from. Mallotus comprises about species, which all occur in mzllotus old world tropics, mainly in asia and oceania. Hydroalcoholic extract of leaves of mallotus oppositifolius moe, a plant used for cns conditions in ghana, was investigated for acute antidepressant effects in the forced swimming. Jun 26, 2019 mallotus oppositifolius can be coppiced and pollarded. Deconstruction of an african folk medicine uncovers a novel. It is known as the kamala tree or red kamala or kumkum tree, due to the fruit covering, which produces a red dye.
From the ethnomedicinally used leaves of mallotus oppositifolius, four acylphloroglucinol derivatives, namely acronyculatin s u and mallotojaponin d 4 were isolated along with seven known compounds 511. The total antioxidant activity of the mallotus oppositifolius mp extract was estimated by the ferric reducing antioxidant power frap assay and the 1,1diphenyl2picrylhydrazyl dpph photometric assay. All free radical scavenging assays were carried out in triplicates and the results shown in the figures represent a mean of the values obtained. An ethanol extract of mallotus oppositifolius geiseler mull. Mallotus oppositifolius is widely distributed and occurs from senegal east to ethiopia and south to angola and mozambique, and also in madagascar. Mallotus philippensis is a plant in the spurge family. Euphorbiaceae is folklorically used to treat diabetic conditions in some parts of nigeria therefore the study, to investigate the extract of the leaves for activities on hyperglycaemia, lipid peroxidation, and increased cholesterol levels in vivo in alloxan diabetic rats as well as its potential antioxidant activity in. Treepie is on kumkum tree or kamala tree mallotus philippensis. Newman osafo, in medicinal plant research in africa, 20. Mallotus oppositifolius mallotus oppositifolius x 3k jpg medias. Callistemenonone a, a novel dearomatic dibenzofurantype.
Mallotus oppositifolius can be coppiced and pollarded. Mallotus oppositifolius is used in ghana for cns disorders but very little. Pdf on jul 1, 2012, fa kabran and others published. Mallotus e um genero botanico pertencente a familia euphorbiaceae algumas plantas deste genero sao encontrados na africa tropical e madagascar. Enter and press button then you will see the osd menu on the monitor.
General information kamala is an evergreen tree, growing up to 25 metres tall. Mallopenins ae, antibacterial phenolic derivatives from. Evaluation of mallotus oppositifolius methanol leaf extract. Mallotus oppositifolius held a place in natural medicine fabricant and farnsworth, 2001. All structured data from the file and property namespaces is available under the creative commons cc0 license. Antiinflammatory and antioxidant activities of mallotus. Is a shrub that is commonly found in drier types of forest secondary growth throughout the west, african region. Aug 01, 2019 mallotus oppositifolius mallotus oppositifolius x 3k jpg medias. A shrub or small tree to m high, common in drier types of forest and in secondary regrowth throughout the region and widespread across tropical africa to madagascar. The herbal medicine, a leaf extract from the shrub mallotus oppositifolius, has been used across africa for centuries. Adongo 2 department of pharmacology, university of ghana medical school, college of health sciences, university of ghana, accra, ghana. Epub oct evaluation of mallotus oppositifolius methanol leaf extract on the. Bluethroated barbet is on bullocks heart fruit annona reticulata.
Research article evaluation of mallotus oppositifolius. At this time of the year you can see numberof butterflies on different flowers and number of birds on flowersfruits. The identification of the phytochemicals in the sample was carried out using a qp2010 gas chromatography with thermal desorption system, td 20 coupled with mass spectroscopy. Gcms analysis for structural identification and bioactive. The herbal medicine, a leaf extract from the shrub mallotus oppositifolius, was previously found to be effective in controlling seizures but the mechanism was unknown. Pdf phytochemical studies and antioxidant properties of. Comparative chemotaxonomic studies on sroti mallotus. Adsorption and inhibitive action of ethanol extracts of mallotus oppositifolius leaves for the corrosion of mild steel in 1m hydrochloric acid solution. A new acylphloroglucinol with a novel architecture including an unprecedented dearomatic dibenzofuran core, named callistemenonone a 1, was isolated from the leaves of callistemon viminalis.
Pdf phytochemical and biological analysis of mallotus. The aqueous and ethanol extracts of the plant show antifungal properties, and anti parasitic activity against blastocystis hominis. The procedures were carried out in triplicates and the mean used in computations. Antiproliferative and antiplasmodial dimeric phloroglucinols. Aug 06, 2019 mallotus oppositifolius is widely distributed and occurs from senegal east to ethiopia and south to angola and mozambique, and also in madagascar. Researchers discover molecular mechanisms of an african. The chromatographic separation of the components of the acetone extract of mallotus philippensis fruits yielded five new phenolic compounds including two chalcones, 1 and 3, a functionalized phloroglucinol, 2, two flavanones, 4 and 5, and six known compounds. A third of the global population relies heavily upon traditional or folk medicines, such as the african shrub mallotus oppositifolius. The antioxidant activity was done in vitro using ferric reducing antioxidant power frap and 1,1diphenyl2hydrazyl dpph spectrophotometric assays. These also show that trevia is embedded within mallotus but. The plant is a common weed of ricefields in bendel state of nigeria 21. The tropical genus mallotus, a member of the family euphorbiaceae, contains.
The antifungal properties of aqueous and ethanol extracts of funtumia elastica and mallotus oppositifolius were carried out using the disc diffusion agar assay. Article pdf available in biochemistry research international 20. Sep 01, 2016 read scientific evidence of plant with a rapidonset and sustained antidepressant effect in a chronic model of depression. Ang mallotus oppositifolius sakop sa kahenera nga mallotus sa kabanay nga euphorbiaceae. Evaluation of mallotus oppositifolius methanol leaf extract on the glycaemia and lipid peroxidation in alloxaninduced diabetic rats. Structures were elucidated by comprehensive spectroscopic analyses and hrms data. Identification and quantification of phytochemical. Antidepressant effects of mallotus oppositifolius in acute. Mallopenins ae, antibacterial phenolic derivatives from the. Home archives vol 11 no 2 2018 articles comparative chemotaxonomic studies on sroti mallotus oppositifolius geiseler mull and velvet bush willow mallotus alternifolius merr. Evaluation of mallotus oppositifolius methanol leaf. The rats were fasted overnight before experimentation but were allowed free.
Notes the plants can range from almost completely glabrous to conspicuously hairy. Mallotus oppositifolius plant is known locally as kafar mutuwaa by hausas, ija by yorubas andnne okpo kirinya by igbos 5. The kcnq1 gene belongs to a large family of genes that provide instructions for making potassium channels. Enhancement of inhibitory neurotransmission and inhibition of. Nwinyi2,5 department of biochemistry, faculty of basic medical sciences, university of calabar, calabar, cross river state, nigeria. Deconstruction of an african folk medicine uncovers a. Euphorbiaceae is folklorically used to treat diabetic conditions in some parts of nigeria therefore the study, to investigate the extract of the leaves for activities on hyperglycaemia, lipid peroxidation, and increased cholesterol levels in vivo in alloxan diabetic rats as well as its potential antioxidant activity in vitro. Hydroalcoholic extract of leaves of mallotus oppositifolius moe, a plant used for cns conditions in ghana, was investigated for acute antidepressant effects in the forced swimming fst and tail suspension tests tst. All the other species are found in east asia, the indian subcontinent, southeast asia, eastern australia, and certain islands of the western pacific.
A maioria sao encontradas no leste e sudeste da asia e, desde a indomalasia ate a nova caledonia e fiji, norte e leste australiano. Scientific evidence of plant with a rapidonset and sustained. Mallotus oppositifolius is widely distributed and occurs from senegal east to ethiopia and south to angola and mozambique, and also in. Jan 16, 2015 mallotus oppositifolius is a tropical plant used to treat many medical conditions in africa. Evaluation of mallotus oppositifolius methanol leaf extract on the glycaemia and lipid peroxidation in. Euphorbiaceae is folklorically used to treat diabetic conditions in some parts of nigeria therefore the study, to investigate the extract of. Pdf evaluation of mallotus oppositifolius methanol leaf extract on. Dmax user guides and product manuals press the sensor number and ent key. Bioassayguided fractionation of an ethanol extract of the leaves and inflorescence of mallotus oppositifolius collected in madagascar led to the isolation of the two new bioactive dimeric phloroglucinols, mallotojaponins b 1 and c 2, together with the known mallotophenone 3. The structures of 15 were confirmed by nmr and mass analyses. Mallotus oppositifolius filed as glinus oppositifolius l. The leaves are taken by hausa in cold infusion for tapeworm 5, 6.
Mallotus is a genus of the spurge family euphorbiaceae first described as a genus in 1790. Pagka karon wala pay siak nga nalista ubos niini niya. Mallotus oppositifolius is a tropical plant used to treat many medical conditions in africa. In west africa it is grown in and around cassava fields to reduce the impact of animals that feed on the leaves, as they prefer mallotus oppositifolius leaves. Mallotus oppositifolius is an open shrub or a tree with elongated branches that can be curved, pendulous or ascending. Scavenging activity of mallotus oppositifolius a kinetic study. Page 26 26 insert cards all the way in to hear click.
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